2qth

Structural highlights

Function

HFLX_SACS2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Specific for GTP.[HAMAP-Rule:MF_00900]^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• GTP-binding protein 3D structures

References

1. ↑ Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van den Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z, van der Oost J. Structure of the ribosome associating GTPase HflX. Proteins. 2010 Feb 15;78(3):705-13. doi: 10.1002/prot.22599. PMID:19787775 doi:http://dx.doi.org/10.1002/prot.22599
2. ↑ Blombach F, Launay H, Zorraquino V, Swarts DC, Cabrita LD, Benelli D, Christodoulou J, Londei P, van der Oost J. An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states. J Bacteriol. 2011 Jun;193(11):2861-7. doi: 10.1128/JB.01552-10. Epub 2011 Apr 8. PMID:21478358 doi:http://dx.doi.org/10.1128/JB.01552-10