4jtm

Structural highlights

Function

GSPD2_ECOH1 Part of a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane (Probable). This subunit forms the outer membrane channel (Probable).^{[1] [2] [3]}

References

1. ↑ Strozen TG, Li G, Howard SP. YghG (GspSbeta) is a novel pilot protein required for localization of the GspSbeta type II secretion system secretin of enterotoxigenic Escherichia coli. Infect Immun. 2012 Aug;80(8):2608-22. doi: 10.1128/IAI.06394-11. Epub 2012 May , 14. PMID:22585966 doi:http://dx.doi.org/10.1128/IAI.06394-11
2. ↑ Korotkov KV, Delarosa JR, Hol WG. A dodecameric ring-like structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli. J Struct Biol. 2013 Jun 29. pii: S1047-8477(13)00168-8. doi:, 10.1016/j.jsb.2013.06.013. PMID:23820381 doi:10.1016/j.jsb.2013.06.013
3. ↑ Yin M, Yan Z, Li X. Structural insight into the assembly of the type II secretion system pilotin-secretin complex from enterotoxigenic Escherichia coli. Nat Microbiol. 2018 May;3(5):581-587. doi: 10.1038/s41564-018-0148-0. Epub 2018, Apr 9. PMID:29632366 doi:http://dx.doi.org/10.1038/s41564-018-0148-0