Structural highlights
Function
ISPH_PLAF7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.[1]
References
- ↑ Rohrich RC, Englert N, Troschke K, Reichenberg A, Hintz M, Seeber F, Balconi E, Aliverti A, Zanetti G, Kohler U, Pfeiffer M, Beck E, Jomaa H, Wiesner J. Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum. FEBS Lett. 2005 Nov 21;579(28):6433-8. doi: 10.1016/j.febslet.2005.10.037. Epub , 2005 Nov 2. PMID:16289098 doi:http://dx.doi.org/10.1016/j.febslet.2005.10.037
