8w9j

Structural highlights

Function

CL12A_HUMAN Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.^{[1] [2]}

References

1. ↑ Marshall AS, Willment JA, Lin HH, Williams DL, Gordon S, Brown GD. Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J Biol Chem. 2004 Apr 9;279(15):14792-802. PMID:14739280 doi:10.1074/jbc.M313127200
2. ↑ Chen CH, Floyd H, Olson NE, Magaletti D, Li C, Draves K, Clark EA. Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood. 2006 Feb 15;107(4):1459-67. PMID:16239426 doi:10.1182/blood-2005-08-3264