5c2y

Structural highlights

Function

RTR1_YEAST RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that dephosphorylates 'Ser-5' of the CTD and regulates RNA polymerase II during the transition from 'Ser-5' to 'Ser-2' phosphorylation.^{[1] [2]}

References

1. ↑ Gibney PA, Fries T, Bailer SM, Morano KA. Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins. Eukaryot Cell. 2008 Jun;7(6):938-48. doi: 10.1128/EC.00042-08. Epub 2008 Apr 11. PMID:18408053 doi:http://dx.doi.org/10.1128/EC.00042-08
2. ↑ Mosley AL, Pattenden SG, Carey M, Venkatesh S, Gilmore JM, Florens L, Workman JL, Washburn MP. Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell. 2009 Apr 24;34(2):168-78. doi: 10.1016/j.molcel.2009.02.025. PMID:19394294 doi:http://dx.doi.org/10.1016/j.molcel.2009.02.025