3t90

Structural highlights

Function

GNA1_ARATH Acetyltransferase involved in UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis. UDP-GlcNAc is an essential metabolite that serves as an initial sugar donor for N-glycan synthesis and thus plays an important role in protein and lipid glycosylation.^{[1] [2]}

References

1. ↑ Riegler H, Herter T, Grishkovskaya I, Lude A, Ryngajllo M, Bolger ME, Essigmann B, Usadel B. Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana. Biochem J. 2012 Apr 15;443(2):427-37. PMID:22329777 doi:10.1042/BJ20112071
2. ↑ Nozaki M, Sugiyama M, Duan J, Uematsu H, Genda T, Sato Y. A missense mutation in the glucosamine-6-phosphate N-acetyltransferase-encoding gene causes temperature-dependent growth defects and ectopic lignin deposition in Arabidopsis. Plant Cell. 2012 Aug;24(8):3366-79. Epub 2012 Aug 28. PMID:22932674 doi:http://dx.doi.org/10.1105/tpc.112.102806