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DPPIV in Humans

spinqualitylabelsall models PDB 6B1E for DPPIV in complex with Vildagliptin Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Introduction 2 Structure 3 Function 4 Catalytic Triad 5 Mechanism 6 Disease 7 Relevance Introduction Image of DPPIV Proline Peptidase Overview Structure [1] Function Catalytic Triad [1] Mechanism Disease Relevance [2]

References

1. ↑ ^{1.0 1.1} Hiramatsu H, Kyono K, Higashiyama Y, Fukushima C, Shima H, Sugiyama S, Inaka K, Yamamoto A, Shimizu R. The structure and function of human dipeptidyl peptidase IV, possessing a unique eight-bladed beta-propeller fold. Biochem Biophys Res Commun. 2003 Mar 21;302(4):849-54. PMID:12646248
2. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

• Karisma Moll
• Merritt Jugo
• Sam Magnabosco