Structural highlights
Function
MACB_AGGAC Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Xu Y, Sim SH, Nam KH, Jin XL, Kim HM, Hwang KY, Lee K, Ha NC. Crystal Structure of the Periplasmic Region of MacB, a Noncanonic ABC Transporter (,). Biochemistry. 2009 May 21. PMID:19432486 doi:10.1021/bi900415t
