4xu4

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Crystal structure of a mycobacterial Insig homolog MvINS from Mycobacterium vanbaalenii at 1.9A resolution

<StructureSection load='4xu4' size='340' side='right'caption='4xu4, resolution 1.90Å' scene=>

Structural highlights

4xu4 is a 1 chain structure with sequence from Mycolicibacterium vanbaalenii PYR-1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.901Å
Ligands:<scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=DDQ:DECYLAMINE-N,N-DIMETHYL-N-OXIDE'>DDQ</scene>
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

INSIG_MYCVP Diacylglycerol-binding protein.[1]

References

  1. Ren R, Zhou X, He Y, Ke M, Wu J, Liu X, Yan C, Wu Y, Gong X, Lei X, Yan SF, Radhakrishnan A, Yan N. PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels. Science. 2015 Jul 10;349(6244):187-91. doi: 10.1126/science.aab1091. PMID:26160948 doi:http://dx.doi.org/10.1126/science.aab1091

Contents

</StructureSection>

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