5x40

Structural highlights

Function

CBIO_RHOCB Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system.^{[1] [2]}

See Also

• ABC transporter 3D structures

References

1. ↑ Rodionov DA, Hebbeln P, Gelfand MS, Eitinger T. Comparative and functional genomic analysis of prokaryotic nickel and cobalt uptake transporters: evidence for a novel group of ATP-binding cassette transporters. J Bacteriol. 2006 Jan;188(1):317-27. PMID:16352848 doi:10.1128/JB.188.1.317-327.2006
2. ↑ Siche S, Neubauer O, Hebbeln P, Eitinger T. A bipartite S unit of an ECF-type cobalt transporter. Res Microbiol. 2010 Dec;161(10):824-9. PMID:20868747 doi:10.1016/j.resmic.2010.09.010