| Structural highlights
8k66 is a 2 chain structure with sequence from Oryza sativa Japonica Group. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| Method: | Electron Microscopy, Resolution 2.53Å |
Ligands: | , , , , , |
Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
HKT21_ORYSJ Seems to be involved in regulation of potassium-sodium homeostasis (PubMed:11489190, PubMed:12795699, PubMed:11959905). Functions as a high-affinity sodium transporter, which mediates increased sodium uptake in roots under potassium deficiency and contributes to sodium accumulation and salt toxicity (PubMed:11489190, PubMed:12795699, PubMed:11959905). Involved in nutritional sodium uptake and distribution in potassium-starved roots to allow plant growth (PubMed:17541409, PubMed:30854552). Functions as a sodium-potassium cotransporter (PubMed:19482918).[1] [2] [3] [4] [5] [6]
References
- ↑ Horie T, Yoshida K, Nakayama H, Yamada K, Oiki S, Shinmyo A. Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa. Plant J. 2001 Jul;27(2):129-38. PMID:11489190 doi:10.1046/j.1365-313x.2001.01077.x
- ↑ Mäser P, Hosoo Y, Goshima S, Horie T, Eckelman B, Yamada K, Yoshida K, Bakker EP, Shinmyo A, Oiki S, Schroeder JI, Uozumi N. Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6428-33. PMID:11959905 doi:10.1073/pnas.082123799
- ↑ Garciadeblás B, Senn ME, Bañuelos MA, Rodríguez-Navarro A. Sodium transport and HKT transporters: the rice model. Plant J. 2003 Jun;34(6):788-801. PMID:12795699 doi:10.1046/j.1365-313x.2003.01764.x
- ↑ Horie T, Costa A, Kim TH, Han MJ, Horie R, Leung HY, Miyao A, Hirochika H, An G, Schroeder JI. Rice OsHKT2;1 transporter mediates large Na+ influx component into K+-starved roots for growth. EMBO J. 2007 Jun 20;26(12):3003-14. PMID:17541409 doi:10.1038/sj.emboj.7601732
- ↑ Jabnoune M, Espeout S, Mieulet D, Fizames C, Verdeil JL, Conéjéro G, Rodríguez-Navarro A, Sentenac H, Guiderdoni E, Abdelly C, Véry AA. Diversity in expression patterns and functional properties in the rice HKT transporter family. Plant Physiol. 2009 Aug;150(4):1955-71. PMID:19482918 doi:10.1104/pp.109.138008
- ↑ Hartley TN, Thomas AS, Maathuis FJM. A role for the OsHKT 2;1 sodium transporter in potassium use efficiency in rice. J Exp Bot. 2020 Jan 7;71(2):699-706. PMID:30854552 doi:10.1093/jxb/erz113
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