5xg7

Structural highlights

Function

PP13_HUMAN Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis.^{[1] [2]}

See Also

• Galectin 3D structures

References

1. ↑ Than NG, Sumegi B, Than GN, Berente Z, Bohn H. Isolation and sequence analysis of a cDNA encoding human placental tissue protein 13 (PP13), a new lysophospholipase, homologue of human eosinophil Charcot-Leyden Crystal protein. Placenta. 1999 Nov;20(8):703-10. PMID:10527825 doi:http://dx.doi.org/10.1053/plac.1999.0436
2. ↑ Than NG, Romero R, Goodman M, Weckle A, Xing J, Dong Z, Xu Y, Tarquini F, Szilagyi A, Gal P, Hou Z, Tarca AL, Kim CJ, Kim JS, Haidarian S, Uddin M, Bohn H, Benirschke K, Santolaya-Forgas J, Grossman LI, Erez O, Hassan SS, Zavodszky P, Papp Z, Wildman DE. A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9731-6. doi:, 10.1073/pnas.0903568106. Epub 2009 Jun 2. PMID:19497882 doi:http://dx.doi.org/10.1073/pnas.0903568106