2rt3

Structural highlights

Function

NRD1_SCHPO Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes until cells reach a critical level of starvation. RNA-binding protein that preferentially binds poly(U).^[1]

References

1. ↑ Jeong HT, Ozoe F, Tanaka K, Nakagawa T, Matsuda H, Kawamukai M. A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe. Genetics. 2004 May;167(1):77-91. PMID:15166138