Structural highlights
Function
OATWY_NEIME Catalyzes the O-acetylation of capsular polymeric sialic acid consisting of polymers of (2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl residues. Shows high substrate specificity toward polymers of sialic acid that contains a large number of residues.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Lee HJ, Rakic B, Gilbert M, Wakarchuk WW, Withers SG, Strynadka NC. Structural and kinetic characterizations of the polysialic acid O-acetyltransferase OatWY from Neisseria meningitidis. J Biol Chem. 2009 Sep 4;284(36):24501-11. Epub 2009 Jun 12. PMID:19525232 doi:10.1074/jbc.M109.006049
