8uzw

Structural highlights

Function

SELA_ECOLI Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. Requires selenophosphate as the selenium-donor molecule.^{[1] [2]}

References

1. ↑ Forchhammer K, Leinfelder W, Boesmiller K, Veprek B, Böck A. Selenocysteine synthase from Escherichia coli. Nucleotide sequence of the gene (selA) and purification of the protein. J Biol Chem. 1991 Apr 5;266(10):6318-23 PMID:2007584
2. ↑ Forchhammer K, Böck A. Selenocysteine synthase from Escherichia coli. Analysis of the reaction sequence. J Biol Chem. 1991 Apr 5;266(10):6324-8 PMID:2007585