Engulfment and cell motility protein 1

Function

Engulfment and cell motility protein 1 (ELMO1) mediates tumour progression by increasing cell motility and inhibiting apoptosis in human colorectal cancer^[1].

Disease

Studies have shown that ELMO1 polymorphism is associated with diabetic nephropathy^[2].

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

3D structures of engulfment and cell motility protein 1

Updated on 13-May-2024

6jpp – hELMO1 RBD domain 1-113 – human - NMR

7y4a – hELMO1 RBD domain + RhoG
2vsz – hELMO1 PH domain 532-727
6tgb – hELMO1 + DOCK2 – Cryo EM
3a98 – hELMO1 PH domain + DOCK2
6tgc – hELMO1 + DOCK2 + Rac1 – Cryo EM
7dpa – hELMO1 + DOCK5 + Rac1 – Cryo EM
6uka – mELMO1 RBD domain + RhoG - mouse