| Structural highlights
Function
CONV_CANCT D-mannose/D-glucose-binding lectin which binds alpha-methyl-D-mannoside, D-mannose and D-glucose in that order (PubMed:24519628, PubMed:27737777). Also binds to serum fetuin and ovalbumin (PubMed:24519628). Has hemagglutinating activity towards rabbit erythrocytes (PubMed:24519628). Is not toxic towards larvae of the brine shrimp Artemia (PubMed:24519628). Induces relaxation in rat endothelized aorta (PubMed:24519628). Shows a transient edematogenic effect in rat (PubMed:27737777).[1] [2]
References
- ↑ Osterne VJ, Santiago MQ, Pinto-Junior VR, Cajazeiras JB, Correia JL, Leitao CC, Carneiro RF, Pereira-Junior FN, Vasconcelos MA, Rocha BA, Assreuy AM, Bringel PH, Nagano CS, Nascimento KS, Cavada BS. Purification, partial characterization, and CNBr-sepharose immobilization of a vasorelaxant glucose/mannose lectin from Canavalia virosa seeds. Appl Biochem Biotechnol. 2014 Apr;172(7):3342-53. doi: 10.1007/s12010-014-0751-3., Epub 2014 Feb 13. PMID:24519628 doi:http://dx.doi.org/10.1007/s12010-014-0751-3
- ↑ Osterne VJ, Silva-Filho JC, Santiago MQ, Pinto-Junior VR, Almeida AC, Barreto AA, Wolin IA, Nascimento AP, Amorim RM, Rocha BA, Delatorre P, Nagano CS, Leal RB, Assreuy AM, Nascimento KS, Cavada BS. Structural characterization of a lectin from Canavalia virosa seeds with inflammatory and cytotoxic activities. Int J Biol Macromol. 2016 Oct 11;94(Pt A):271-282. doi:, 10.1016/j.ijbiomac.2016.10.020. PMID:27737777 doi:http://dx.doi.org/10.1016/j.ijbiomac.2016.10.020
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