ER-resident protein

From Proteopedia

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spinqualitylabelsall models Mouse ERp5 (PDB code 3apo) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function ER-resident proteins (ERp) are proteins which are retained by the endoplasmic reticulum[1]. ERp18 monitors control ensuring optimal processing of ATF6alpha following its trafficking to the Golgi[2]. ERp27 functions a a disulphide isomerase[3]. For details on ERdj5 see Molecular Playground/ERDj5. Structural insights The .

3D Structures of ER-resident protein

Updated on 19-June-2024

References

1. ↑ Hagiwara M, Maegawa K, Suzuki M, Ushioda R, Araki K, Matsumoto Y, Hoseki J, Nagata K, Inaba K. Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5. Mol Cell. 2011 Feb 18;41(4):432-44. PMID:21329881 doi:10.1016/j.molcel.2011.01.021
2. ↑ Oka OB, van Lith M, Rudolf J, Tungkum W, Pringle MA, Bulleid NJ. ERp18 regulates activation of ATF6α during unfolded protein response. EMBO J. 2019 Aug 1;38(15):e100990. PMID:31368601 doi:10.15252/embj.2018100990
3. ↑ Alanen HI, Williamson RA, Howard MJ, Hatahet FS, Salo KE, Kauppila A, Kellokumpu S, Ruddock LW. ERp27, a new non-catalytic endoplasmic reticulum-located human protein disulfide isomerase family member, interacts with ERp57. J Biol Chem. 2006 Nov 3;281(44):33727-38. PMID:16940051 doi:10.1074/jbc.M604314200