1ns5

Structural highlights

Function

RLMH_ECOLI Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. Specific for fully assembled 70S ribosomes.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S. YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA. RNA. 2008 Oct;14(10):2234-44. Epub 2008 Aug 28. PMID:18755835 doi:http://dx.doi.org/rna.1198108
2. ↑ Ero R, Peil L, Liiv A, Remme J. Identification of pseudouridine methyltransferase in Escherichia coli. RNA. 2008 Oct;14(10):2223-33. Epub 2008 Aug 28. PMID:18755836 doi:http://dx.doi.org/rna.1186608