1xud

From Proteopedia

Revision as of 18:04, 12 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1xud.gif

1xud, resolution 1.800Å

Drag the structure with the mouse to rotate

Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor

Overview

The paradigm for matrix metalloprotease inhibition combines active site, tailoring and catalytic zinc ligation. But, selectivity has been, difficult. Now, Engel et al. present novel compounds, completely selective, for MMP-13, with a unique binding mode.

About this Structure

1XUD is a Single protein structure of sequence from Homo sapiens with ZN, CA and PB4 as ligands. Full crystallographic information is available from OCA.

Reference

Making a new turn in matrix metalloprotease inhibition., Wasserman ZR, Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640

Page seeded by OCA on Mon Nov 12 20:11:11 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xud"
Personal tools