1urr
From Proteopedia
A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)
Overview
Analysis of the Drosophila melanogaster EST database led to the discovery and cloning of a novel acylphosphatase. The CG18505 gene coding for a new enzyme (AcPDro2) is clearly distinct from the previously described CG16870Acyp gene, which also codes for a D. melanogaster acylphosphatase (AcPDro). The putative catalytic residues, together with residues held to stabilize the acylphosphatase fold, are conserved in the two encoded proteins. Crystals of AcPDro2, which belong to the trigonal space group P3(1)21, with unit-cell parameters a = b = 45.8, c = 98.6 angstroms, gamma = 120 degrees, allowed the solution of the protein structure by molecular replacement and its refinement to 1.5 angstroms resolution. The AcPDro2 active-site structure is discussed.
About this Structure
1URR is a Single protein structure of sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase., Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:15159593 Page seeded by OCA on Sat May 3 11:36:00 2008
