8yeb

Structural highlights

Function

KET3E_ARTGO Catalyzes the reversible C-3 epimerization of several ketoses. Shows the highest enzymatic activity for the epimerization of L-ribulose to L-xylulose. Is also able to convert D-allulose (also known as D-psicose) to D-fructose and, to a lesser extent, L-tagatose to L-sorbose, D-ribulose to D-xylulose, L-allulose to L-fructose and D-tagatose to D-sorbose.^{[1] [2]}

References

1. ↑ Yoshihara A, Kozakai T, Shintani T, Matsutani R, Ohtani K, Iida T, Akimitsu K, Izumori K, Gullapalli PK. Purification and characterization of d-allulose 3-epimerase derived from Arthrobacter globiformis M30, a GRAS microorganism. J Biosci Bioeng. 2017 Feb;123(2):170-176. PMID:27713017 doi:10.1016/j.jbiosc.2016.09.004
2. ↑ Yoshida H, Yoshihara A, Gullapalli PK, Ohtani K, Akimitsu K, Izumori K, Kamitori S. X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D-allulose from D-fructose. Acta Crystallogr F Struct Biol Commun. 2018 Oct 1;74(Pt 10):669-676. doi:, 10.1107/S2053230X18011706. Epub 2018 Sep 21. PMID:30279320 doi:http://dx.doi.org/10.1107/S2053230X18011706