From Proteopedia

proteopedia linkproteopedia link

Syn-F4, a Ferric Enterobactin Esterase

spinqualitylabelsall models Syn-F4 PDB: 8H7C Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Introduction 1.1 Ligand 2 Function 2.1 Active Site 3 Mechanism 4 Relevance Introduction Figure 1. Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4 Ligand Function Active Site Here is a nice view of the [1] [2] Mechanism Relevance

References

1. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
2. ↑ Kurihara K, Umezawa K, Donnelly AE, Sperling B, Liao G, Hecht MH, Arai R. Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2218281120. PMID:37695900 doi:10.1073/pnas.2218281120

Student Contributors

• Milica Nenadovich
• Reesha Bhagat