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Introduction
Structural Overview
Catalytic Triad
Ligand Binding Site
Mutations
F243
F243I
F243W
T96
T96M
Located within the core of the protein. Replacing Threonine with methionine, reduces polarity as well as increasing hydrophobicity. This change leads to an overall improvement in the packing of the hydrophobic core of the protein.
Y127
N246
S283 & D238
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
