Structural highlights
Function
SAT_CAEEL Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283700). Substrate specificity: thialysine > O-(2-aminoethyl)-L-serine > S-(2-aminoethyl)-D,L-homocysteine (PubMed:15283700). Does not act on polyamines, such as spermidine and spermine, nor on diamines putrescine and cadaverine (PubMed:15283700).[1]
References
- ↑ Abo-Dalo B, Ndjonka D, Pinnen F, Liebau E, Lüersen K. A novel member of the GCN5-related N-acetyltransferase superfamily from Caenorhabditis elegans preferentially catalyses the N-acetylation of thialysine [S-(2-aminoethyl)-L-cysteine]. Biochem J. 2004 Nov 15;384(Pt 1):129-37. PMID:15283700 doi:10.1042/BJ20040789
