9czs

Structural highlights

Function

LDB2_MOUSE Transcription cofactor (PubMed:9192866). Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors (PubMed:9192866).^[1] Regulates the transcriptional activity of LIM-containing proteins such as LHX3 or PITX1.^[2]

References

1. ↑ Bach I, Carriere C, Ostendorff HP, Andersen B, Rosenfeld MG. A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev. 1997 Jun 1;11(11):1370-80. PMID:9192866
2. ↑ Bach I, Carriere C, Ostendorff HP, Andersen B, Rosenfeld MG. A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev. 1997 Jun 1;11(11):1370-80. PMID:9192866