Structural highlights
Function
GUAB1_MYCS2 Involved in the purine-salvage pathway (PubMed:35338694). Catalyzes the NADPH-dependent conversion of GMP to IMP (PubMed:35338694). Is not essential for viability, but may contribute to the regulation of the purine nucleotide pool by recycling GMP to IMP (PubMed:35338694).[1]
References
- ↑ Knejzlik Z, Dolezal M, Herkommerova K, Clarova K, Klima M, Dedola M, Zbornikova E, Rejman D, Pichova I. The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-beta-synthase domain. FEBS J. 2022 Mar 26. doi: 10.1111/febs.16448. PMID:35338694 doi:http://dx.doi.org/10.1111/febs.16448
