SLC37A2
From Proteopedia
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Contents |
SLC37A4 (glucose-6-phosphate transporter)
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Function
SLC37A4 (solute carrier family 37 member 4), also known as G6PT1, is the most studied G6PT family member and is widely expressed in various tissues and organs, especially the main gluconeogenic organs, including the liver, kidney, and intestine. In these organs, G6PT1 and G6PC1 form the functional complex G6Pase-α, which is essential for maintaining blood glucose homeostasis, whereas in neutrophils and macrophages, G6PT1 associates with G6PC3 to form the G6Pase-β complex, which regulates energetic homeostasis and neutrophil function[3].
Disease
Relevance
Structural highlights
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Unknown PubmedID 1005677912539
