1xud
From Proteopedia
Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor
Overview
The paradigm for matrix metalloprotease inhibition combines active site tailoring and catalytic zinc ligation. But, selectivity has been difficult. Now, Engel et al. present novel compounds, completely selective for MMP-13, with a unique binding mode.
About this Structure
1XUD is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Making a new turn in matrix metalloprotease inhibition., Wasserman ZR, Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 Page seeded by OCA on Sat May 3 15:31:17 2008
