1yhd
From Proteopedia
The solution structure of YGGX from Escherichia Coli
Overview
YggX is a highly conserved protein found only in eubacteria and is proposed to be involved in the bacterial response to oxidative stress. Here we report the solution structure of YggX from Escherichia coli determined by nuclear magnetic resonance spectroscopy. The structure of YggX displays a fold consisting of two N-terminal antiparallel beta-sheets and three alpha-helices, which shares significant structural similarity to the crystal structure of a hypothetical protein PA5148 from Pseudomonas aeruginosa. Previous studies propose YggX as an iron binding protein that is involved in cellular iron trafficking. Our data indicate that the protein alone does not bind iron in vitro, suggesting other cofactors or different conditions may be necessary for metal binding.
About this Structure
1YHD is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
The solution structure of the oxidative stress-related protein YggX from Escherichia coli., Osborne MJ, Siddiqui N, Landgraf D, Pomposiello PJ, Gehring K, Protein Sci. 2005 Jun;14(6):1673-8. Epub 2005 May 9. PMID:15883188 Page seeded by OCA on Sat May 3 16:19:04 2008
