1zoq

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Template:STRUCTURE 1zoq

IRF3-CBP complex


Overview

Interferon regulatory factor (IRF) 3 plays a critical role in triggering the activation of interferon antiviral genes. The structure of IRF-3 in association with the CBP/p300 coactivator by in this issue of Structure illuminates the mechanism of IRF activation and the structural flexibilities inherent in CBP/p300.

About this Structure

1ZOQ is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

IRF-3 releases its inhibitions., Hiscott J, Lin R, Structure. 2005 Sep;13(9):1235-6. PMID:16154077 Page seeded by OCA on Sat May 3 17:53:17 2008

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