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1ndo
From Proteopedia
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NAPTHALENE 1,2-DIOXYGENASE
Overview
BACKGROUND: Pseudomonas sp. NCIB 9816-4 utilizes a multicomponent enzyme, system to oxidize naphthalene to, (+)-cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene. The enzyme component, catalyzing this reaction, naphthalene 1,2-dioxygenase (NDO), belongs to a, family of aromatic-ring-hydroxylating dioxygenases that oxidize aromatic, hydrocarbons and related compounds to cis-arene diols. These enzymes, utilize a mononuclear non-heme iron center to catalyze the addition of, dioxygen to their respective substrates. The present study was conducted, to provide essential structural information necessary for elucidating the, mechanism of action of NDO. RESULTS: The three-dimensional structure of, NDO has been determined at 2.25 A resolution. The molecule is an alpha 3, beta 3 hexamer. The alpha ... [(full description)]
About this Structure
1NDO is a [Protein complex] structure of sequences from [Pseudomonas putida] with FE and FES as [ligands]. Active as [[1]], with EC number [1.14.12.12]. Full crystallographic information is available from [OCA].
Reference
Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase., Kauppi B, Lee K, Carredano E, Parales RE, Gibson DT, Eklund H, Ramaswamy S, Structure. 1998 May 15;6(5):571-86. PMID:9634695
Page seeded by OCA on Mon Oct 29 18:49:05 2007
