We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
217d
From Proteopedia
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Overview
Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.
About this Structure
Full crystallographic information is available from OCA.
Reference
Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741 Page seeded by OCA on Sat May 3 18:19:12 2008
