2asw

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Template:STRUCTURE 2asw

The solution structure of the hamp domain of the hypothetical transmembrane receptor Af1503


Overview

The HAMP domain is present in a large number of transmembrane proteins in prokaryotes including histidine kinases, adenylyl cyclases, chemotaxis receptors, and phosphatases. In this issue of Cell, Hulko et al. (2006) report the NMR structure of a HAMP domain and present data suggesting that it transduces signals through a simple rotation of its four-helix parallel coiled coil.

About this Structure

2ASW is a Single protein structure of sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.

Reference

Signaling by transmembrane proteins shifts gears., Inouye M, Cell. 2006 Sep 8;126(5):829-31. PMID:16959559 Page seeded by OCA on Sat May 3 19:26:25 2008

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