2aub

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Template:STRUCTURE 2aub

Lysozyme structure derived from thin-film-based crystals


Overview

The present report is dedicated to a systematic comparison of crystal structures produced by the nanobiofilm template method and by the classical hanging-drop vapour-diffusion method. Crystals grown by the innovative nanostructured template method appear indeed radiation-resistant even in the presence of a third-generation highly focused beam at the European Synchrotron Radiation Facility. The implications of this finding for protein crystallography are discussed here in terms of water redistribution and of the detailed atomic resolution comparative studies of the two crystal structures with or without nanobiofilm template, as emerging also from circular-dichroism and thermal denaturation studies.

About this Structure

2AUB is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Comparison of lysozyme structures derived from thin-film-based and classical crystals., Pechkova E, Sivozhelezov V, Tropiano G, Fiordoro S, Nicolini C, Acta Crystallogr D Biol Crystallogr. 2005 Jun;61(Pt 6):803-8. Epub 2005, May 26. PMID:15930644 Page seeded by OCA on Sat May 3 19:29:09 2008

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