2jhc

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Image:2jhc.gif

Template:STRUCTURE 2jhc

THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JHC is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654 Page seeded by OCA on Sun May 4 08:55:13 2008

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