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2qux

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Revision as of 12:44, 4 May 2008 by OCA (Talk | contribs)
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Template:STRUCTURE 2qux

PP7 coat protein dimer in complex with RNA hairpin


Overview

The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.

About this Structure

2QUX is a Single protein structure of sequence from Pseudomonas phage pp7. Full crystallographic information is available from OCA.

Reference

Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080 Page seeded by OCA on Sun May 4 15:44:07 2008

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