This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1aft
From Proteopedia
|
SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES
Overview
The structure of peptide N-AcYTLDADF when bound to the large subunit of, mouse ribonucleotide reductase has been elucidated by transfer NOE. This, structure suggests a general design for type 1 RR inhibitors.
About this Structure
1AFT is a Single protein structure of sequence from [1] with ACE as ligand. Active as Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1 Full crystallographic information is available from OCA.
Reference
NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:7583667
Page seeded by OCA on Tue Nov 20 10:49:18 2007
