2odj

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Template:STRUCTURE 2odj

Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa


Overview

OprD proteins form a large family of substrate-specific outer-membrane channels in Gram-negative bacteria. We report here the X-ray crystal structure of OprD from Pseudomonas aeruginosa, which reveals a monomeric 18-stranded beta-barrel characterized by a very narrow pore constriction, with a positively charged basic ladder on one side and an electronegative pocket on the other side. The location of highly conserved residues in OprD suggests that the structure represents the general architecture of OprD channels.

About this Structure

2ODJ is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

Structural insight into OprD substrate specificity., Biswas S, Mohammad MM, Patel DR, Movileanu L, van den Berg B, Nat Struct Mol Biol. 2007 Nov;14(11):1108-9. Epub 2007 Oct 21. PMID:17952093 Page seeded by OCA on Wed May 7 08:49:46 2008

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