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1opl

From Proteopedia

Revision as of 14:47, 26 June 2008 by OCA (Talk | contribs)

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Image:1opl.png

1opl, resolution 3.42Å ()

Ligands:

Gene:

Abl (Homo sapiens)

Activity:

Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2

Related:

1opj, 1opk

Structural annotation:
Resources:	CATH : 1Opla04, 1Opla03, 1Opla02, 1Opla01 InterPro : Ipr011009, Ipr008266, Ipr015015, Ipr001245, Ipr000980, Ipr000719, Ipr001452 Pfam : PF07714, PF00018, PF00017 SCOP : d1opla3, d1opla2, d1opla1, d1oplb1, d1oplb2 UniProt : P00519

Functional annotation:
Cellular component:	cytoskeleton cytoplasm nucleus
Biological process:	protein amino acid phosphorylation DNA damage response, signal transduction resulting in induction of apoptosis intracellular signaling cascade S-phase-specific transcription in mitotic cell cycle cell adhesion actin cytoskeleton organization and biogenesis mismatch repair regulation of transcription, DNA-dependent peptidyl-tyrosine phosphorylation protein modification process
Molecular function:	transferase activity protein C-terminus binding nucleotide binding kinase activity metal ion binding manganese ion binding magnesium ion binding protein kinase activity ATP binding protein-tyrosine kinase activity DNA binding protein binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Structural basis for the auto-inhibition of c-Abl tyrosine kinase

Template:ABSTRACT 12654251

About this Structure

1OPL is a Single protein structure of sequence from Homo sapiens. The following page contains interesting information on the relation of 1OPL with [Src Tyrosine Kinase]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:47:58 2008

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1opl

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About this Structure

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