1ecr

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Image:1ecr.gif

1ecr, resolution 2.700Å

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ESCHERICHIA COLI REPLICATION TERMINATOR PROTEIN (TUS) COMPLEXED WITH DNA

Overview

The crystal structure of the Escherichia coli replication-terminator, protein (Tus) bound to terminus-site (Ter) DNA has been determined at 2.7, A resolution. The Tus protein folds into a previously undescribed, architecture divided into two domains by a central basic cleft. This cleft, accommodates locally deformed B-form Ter DNA and makes extensive contacts, with the major groove, mainly through two interdomain beta-strands. The, unusual structural features of this complex may explain how the, replication fork is halted in only one direction.

About this Structure

1ECR is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of a replication-terminator protein complexed with DNA., Kamada K, Horiuchi T, Ohsumi K, Shimamoto N, Morikawa K, Nature. 1996 Oct 17;383(6601):598-603. PMID:8857533

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