1dq8

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spinqualitylabelsall models PDB ID 1dq8 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1dq8, resolution 2.10Å ()
Ligands:	, ,
Activity:	Hydroxymethylglutaryl-CoA reductase (NADPH), with EC number 1.1.1.34
Structural annotation: Resources: CATH : 1Dq8A03, 1Dq8A02, 1Dq8A01, 1Dq8B02, 1Dq8B01, 1Dq8B03, 1Dq8C02, 1Dq8C01, 1Dq8C03, 1Dq8D03, 1Dq8D02, 1Dq8D01 InterPro : Ipr009023, Ipr000731, Ipr002202, Ipr004816, Ipr004554, Ipr009029 Pfam : PF00368 SCOP : d1dq8a4, d1dq8a1, d1dq8b4, d1dq8b1, d1dq8c1, d1dq8c4, d1dq8d1, d1dq8d4 UniProt : P04035
Functional annotation: Cellular component: membrane fraction endoplasmic reticulum endoplasmic reticulum membrane membrane peroxisome integral to membrane Biological process: germ cell migration lipid metabolic process cholesterol biosynthetic process gonad development sterol biosynthetic process cholesterol metabolic process lipid biosynthetic process biosynthetic process steroid biosynthetic process Molecular function: oxidoreductase activity hydroxymethylglutaryl-CoA reductase (NADPH) activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG AND COA

Template:ABSTRACT PUBMED 10698924

About this Structure

1DQ8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis., Istvan ES, Palnitkar M, Buchanan SK, Deisenhofer J, EMBO J. 2000 Mar 1;19(5):819-30. PMID:10698924

Page seeded by OCA on Mon Jun 30 23:27:14 2008