1e9c

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Template:STRUCTURE 1e9c

MUTANT HUMAN THYMIDYLATE KINASE COMPLEXED WITH TMP AND APPNP

Template:ABSTRACT PUBMED 11071809

About this Structure

1E9C is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP., Ostermann N, Lavie A, Padiyar S, Brundiers R, Veit T, Reinstein J, Goody RS, Konrad M, Schlichting I, J Mol Biol. 2000 Nov 17;304(1):43-53. PMID:11071809

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