This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1ex8
From Proteopedia
CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR
Template:ABSTRACT PUBMED 11311059
About this Structure
1EX8 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies., Shi G, Blaszczyk J, Ji X, Yan H, J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059
Page seeded by OCA on Tue Jul 1 02:09:31 2008
Categories: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | Escherichia coli | Single protein | Blaszczyk, J. | Ji, X. | Active-site architecture | Antimicrobial agent | Atp | Bisubstrate-mimicking inhibitor | Drug design | Folate | Hppk | Pterin | Pyrophosphokinase | Pyrophosphoryl transfer | Substrate specificity | X-ray crystallography
