1gfw

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Template:STRUCTURE 1gfw

THE 2.8 ANGSTROM CRYSTAL STRUCTURE OF CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR.

Template:ABSTRACT PUBMED 10821855

About this Structure

1GFW is a Protein complex structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 1qa8. Full crystallographic information is available from OCA.

Reference

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality., Lee D, Long SA, Adams JL, Chan G, Vaidya KS, Francis TA, Kikly K, Winkler JD, Sung CM, Debouck C, Richardson S, Levy MA, DeWolf WE Jr, Keller PM, Tomaszek T, Head MS, Ryan MD, Haltiwanger RC, Liang PH, Janson CA, McDevitt PJ, Johanson K, Concha NO, Chan W, Abdel-Meguid SS, Badger AM, Lark MW, Nadeau DP, Suva LJ, Gowen M, Nuttall ME, J Biol Chem. 2000 May 26;275(21):16007-14. PMID:10821855

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