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1iiq

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Template:STRUCTURE 1iiq

CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR

Template:ABSTRACT PUBMED 11906284

About this Structure

1IIQ is a Single protein structure of sequence from Human immunodeficiency virus - 1. Full crystallographic information is available from OCA.

Reference

Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor., Dohnalek J, Hasek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlacek J, Fabry M, J Med Chem. 2002 Mar 28;45(7):1432-8. PMID:11906284

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