1h3z
From Proteopedia
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SOLUTION STRUCTURE OF A PWWP DOMAIN FROM SCHIZOSACCHAROMYCES POMBE
Overview
The PWWP domain is a ubiquitous eukaryotic protein module characterised by, a region of sequence similarity of approximately 80 amino acids containing, a highly conserved PWWP motif. It is frequently found in proteins, associated with chromatin. We have determined the structure of a PWWP, domain from the S. pombe protein SPBC215.07c using NMR spectroscopy. The, structure is composed of a five stranded beta barrel followed by two alpha, helices. Comparison to the recently reported structure of a homologous, domain from the mammalian DNA methyltransferase Dnmt3b reveals substantial, differences both in the C-terminal helical region and in the PWWP motif.
About this Structure
1H3Z is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.
Reference
Structural variation in PWWP domains., Slater LM, Allen MD, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):571-6. PMID:12842472
Page seeded by OCA on Tue Nov 20 16:24:48 2007
