1hst

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Image:1hst.gif

1hst, resolution 2.6Å

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CRYSTAL STRUCTURE OF GLOBULAR DOMAIN OF HISTONE H5 AND ITS IMPLICATIONS FOR NUCLEOSOME BINDING

Overview

The structure of GH5, the globular domain of the linker histone H5, has, been solved to 2.5 A resolution by multiwavelength anomalous diffraction, on crystals of the selenomethionyl protein. The structure shows a striking, similarity to the DNA-binding domain of the catabolite gene activator, protein CAP, thereby providing a possible model for the binding of GH5 to, DNA.

About this Structure

1HST is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding., Ramakrishnan V, Finch JT, Graziano V, Lee PL, Sweet RM, Nature. 1993 Mar 18;362(6417):219-23. PMID:8384699

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