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1m5i

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Revision as of 20:15, 2 July 2008 by OCA (Talk | contribs)
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Template:STRUCTURE 1m5i

Contents

Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC

Template:ABSTRACT PUBMED 12070164

Disease

Known disease associated with this structure: Adenoma, periampullary OMIM:[611731], Adenomatous polyposis coli OMIM:[611731], Brain tumor-polyposis syndrome 2 OMIM:[611731], Colorectal cancer, somatic OMIM:[611731], Desmoid disease, hereditary OMIM:[611731], Gardner syndrome OMIM:[611731], Gastric cancer, somatic OMIM:[611731], Hepatoblastoma OMIM:[611731]

About this Structure

1M5I is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1)., Tickenbrock L, Cramer J, Vetter IR, Muller O, J Biol Chem. 2002 Aug 30;277(35):32332-8. Epub 2002 Jun 17. PMID:12070164

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