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1ixh

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Revision as of 15:37, 20 November 2007 by OCA (Talk | contribs)
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Image:1ixh.gif

1ixh, resolution 0.98Å

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PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE

Overview

A very short hydrogen bond between an Asp and a phosphate is established, in two high resolution structures (0.98 and 1.05 A). A mutant complex that, changes the Asp to an Asn, which forms a normal hydrogen bond, has a, similar free energy of binding to the wild type complex, suggesting that, the contribution of the short hydrogen bond is not extraordinarily strong.

About this Structure

1IXH is a Single protein structure of sequence from Escherichia coli with PO4 as ligand. Full crystallographic information is available from OCA.

Reference

A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes., Wang Z, Luecke H, Yao N, Quiocho FA, Nat Struct Biol. 1997 Jul;4(7):519-22. PMID:9228942

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